Antitumor effect of manumycin on colorectal cancer cells by increasing the reactive oxygen species production and blocking PI3K-AKT pathway

Manumycin is a natural, well-tolerated microbial metabolite and is regarded as a farnesyltransferase inhibitor. Some data suggest that manumycin inhibits proliferation of diverse cancer cells through various pathways. However, the antitumor effect of manumycin on colorectal cancer (CRC) remains unkn...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Zhang, Jingyu, Jiang, Hua, Xie, Li, Hu, Jing, Li, Li, Yang, Mi, Cheng, Lei, Liu, Baorui, Qian, Xiaoping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2016
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888730/
https://ncbi.nlm.nih.gov/pubmed/27307747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102408
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk