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Withaferin A-Caused Production of Intracellular Reactive Oxygen Species Modulates Apoptosis via PI3K/Akt and JNKinase in Rabbit Articular Chondrocytes

Withaferin A (WFA) is known as a constituent of Ayurvedic medicinal plant, Withania somnifera, and has been used for thousands of years. Although WFA has been used for the treatment of osteoarthritis (OA) and has a wide range of biochemical and pharmacologic activities, there are no findings suggest...

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Autors principals: Yu, Seon-Mi, Kim, Song-Ja
Format: Artigo
Idioma:Inglês
Publicat: The Korean Academy of Medical Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129194/
https://ncbi.nlm.nih.gov/pubmed/25120312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2014.29.8.1042
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