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Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice

The related Rab GTPase-activating proteins (Rab GAPs) AS160 and Tbc1d1 regulate the trafficking of the glucose transporter GLUT4 that controls glucose uptake in muscle and fat cells and glucose homeostasis. AS160- and Tbc1d1-deficient mice exhibit different adipocyte- and skeletal muscle-specific de...

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Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Hargett, Stefan R., Walker, Natalie N., Keller, Susanna R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888528/
https://ncbi.nlm.nih.gov/pubmed/26625902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00342.2015
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