Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence

Among the several mechanisms that contribute to MDR (multidrug resistance), the overexpression of drug-efflux pumps belonging to the ABC (ATP-binding cassette) superfamily is the most frequent cause of resistance to antifungal agents. The multidrug transporter proteins Cdr1p and Cdr2p of the ABCG su...

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Udgivet i:Biochem J
Main Authors: Khandelwal, Nitesh Kumar, Kaemmer, Philipp, Förster, Toni M., Singh, Ashutosh, Coste, Alix T., Andes, David R., Hube, Bernhard, Sanglard, Dominique, Chauhan, Neeraj, Kaur, Rupinder, d'Enfert, Christophe, Mondal, Alok Kumar, Prasad, Rajendra
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888455/
https://ncbi.nlm.nih.gov/pubmed/27026051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160024
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