Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates

TAC1 (for transcriptional activator of CDR genes) is critical for the upregulation of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida albicans. While a wild-type TAC1 allele drives high expression of CDR1/2 in response to inducers, we showed previously that TAC1 can be...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Coste, Alix, Selmecki, Anna, Forche, Anja, Diogo, Dorothée, Bougnoux, Marie-Elisabeth, d'Enfert, Christophe, Berman, Judith, Sanglard, Dominique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043391/
https://ncbi.nlm.nih.gov/pubmed/17693596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00151-07
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg