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Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates
TAC1 (for transcriptional activator of CDR genes) is critical for the upregulation of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida albicans. While a wild-type TAC1 allele drives high expression of CDR1/2 in response to inducers, we showed previously that TAC1 can be...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2043391/ https://ncbi.nlm.nih.gov/pubmed/17693596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00151-07 |
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