Impact of HCV core gene quasispecies on hepatocellular carcinoma risk among HALT-C trial patients

Mutations at positions 70 and/or 91 in the core protein of genotype-1b, hepatitis C virus (HCV) are associated with hepatocellular carcinoma (HCC) risk in Asian patients. To evaluate this in a US population, the relationship between the percentage of 70 and/or 91 mutant HCV quasispecies in baseline...

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Pubblicato in:Sci Rep
Autori principali: El-Shamy, Ahmed, Pendleton, Matthew, Eng, Francis J., Doyle, Erin H., Bashir, Ali, Branch, Andrea D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887904/
https://ncbi.nlm.nih.gov/pubmed/27246310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27025
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