TRPM7 kinase activity regulates murine mast cell degranulation

KEY POINTS: The Mg(2+) and Ca(2+) conducting transient receptor potential melastatin 7 (TRPM7) channel–enzyme (chanzyme) has been implicated in immune cell function. Mice heterozygous for a TRPM7 kinase deletion are hyperallergic, while mice with a single point mutation at amino acid 1648, silencing...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Physiol
Prif Awduron: Zierler, Susanna, Sumoza‐Toledo, Adriana, Suzuki, Sayuri, Dúill, Fionán Ó, Ryazanova, Lillia V., Penner, Reinhold, Ryazanov, Alexey G., Fleig, Andrea
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Molecular and Cellular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887679/
https://ncbi.nlm.nih.gov/pubmed/26660477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271564
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