Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis

Rheumatoid arthritis is one of the most common autoimmune diseases. Many antioxidants have been tested in arthritis, but their efficacy was, at best, marginal. In this study, a novel mitochondria-targeted antioxidant, plastoquinonyl-decyl-triphenylphosphonium bromide (SkQ1), was tested in vivo to pr...

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Dades bibliogràfiques
Publicat a:Oxid Med Cell Longev
Autors principals: Andreev-Andrievskiy, Alexander A., Kolosova, Nataliya G., Stefanova, Natalia A., Lovat, Maxim V., Egorov, Maxim V., Manskikh, Vasily N., Zinovkin, Roman A., Galkin, Ivan I., Prikhodko, Anastasia S., Skulachev, Maxim V., Lukashev, Alexander N.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887630/
https://ncbi.nlm.nih.gov/pubmed/27293517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8703645
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