Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis

Rheumatoid arthritis is one of the most common autoimmune diseases. Many antioxidants have been tested in arthritis, but their efficacy was, at best, marginal. In this study, a novel mitochondria-targeted antioxidant, plastoquinonyl-decyl-triphenylphosphonium bromide (SkQ1), was tested in vivo to pr...

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Pubblicato in:Oxid Med Cell Longev
Autori principali: Andreev-Andrievskiy, Alexander A., Kolosova, Nataliya G., Stefanova, Natalia A., Lovat, Maxim V., Egorov, Maxim V., Manskikh, Vasily N., Zinovkin, Roman A., Galkin, Ivan I., Prikhodko, Anastasia S., Skulachev, Maxim V., Lukashev, Alexander N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887630/
https://ncbi.nlm.nih.gov/pubmed/27293517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8703645
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