Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis

Rheumatoid arthritis is one of the most common autoimmune diseases. Many antioxidants have been tested in arthritis, but their efficacy was, at best, marginal. In this study, a novel mitochondria-targeted antioxidant, plastoquinonyl-decyl-triphenylphosphonium bromide (SkQ1), was tested in vivo to pr...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Andreev-Andrievskiy, Alexander A., Kolosova, Nataliya G., Stefanova, Natalia A., Lovat, Maxim V., Egorov, Maxim V., Manskikh, Vasily N., Zinovkin, Roman A., Galkin, Ivan I., Prikhodko, Anastasia S., Skulachev, Maxim V., Lukashev, Alexander N.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887630/
https://ncbi.nlm.nih.gov/pubmed/27293517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8703645
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