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Decreasing Striatopallidal Pathway Function Enhances Motivation by Energizing the Initiation of Goal-Directed Action
Altered dopamine D2 receptor (D2R) binding in the striatum has been associated with abnormal motivation in neuropsychiatric disorders, including schizophrenia. Here, we tested whether motivational deficits observed in mice with upregulated D2Rs (D2R-OE(dev) mice) are reversed by decreasing function...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887564/ https://ncbi.nlm.nih.gov/pubmed/27251620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0444-16.2016 |
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