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Extracellular interactions and ligand degradation shape the nodal morphogen gradient

The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the Nodal gradient include diffusivity, ligand processi...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Wang, Yin, Wang, Xi, Wohland, Thorsten, Sampath, Karuna
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887204/
https://ncbi.nlm.nih.gov/pubmed/27101364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13879
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