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Extracellular interactions and ligand degradation shape the nodal morphogen gradient

The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the Nodal gradient include diffusivity, ligand processi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Yin, Wang, Xi, Wohland, Thorsten, Sampath, Karuna
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887204/
https://ncbi.nlm.nih.gov/pubmed/27101364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13879
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