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Response to Nodal morphogen gradient is determined by the kinetics of target gene induction

Morphogen gradients expose cells to different signal concentrations and induce target genes with different ranges of expression. To determine how the Nodal morphogen gradient induces distinct gene expression patterns during zebrafish embryogenesis, we measured the activation dynamics of the signal t...

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Pubblicato in:eLife
Autori principali: Dubrulle, Julien, Jordan, Benjamin M, Akhmetova, Laila, Farrell, Jeffrey A, Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Schier, Alexander F
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395910/
https://ncbi.nlm.nih.gov/pubmed/25869585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05042
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