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Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a devastating multisystemic autoimmune disorder. However, the molecular mechanisms underlying its pathogenesis remain elusive. Some patients with Noonan syndrome, a congenital disorder predominantly caused by gain-of-function mutations in the protein tyrosine ph...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887187/ https://ncbi.nlm.nih.gov/pubmed/27183387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87037 |
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