Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis

Liver glycogen is important for the counterregulation of hypoglycemia and is reduced in individuals with type 1 diabetes (T1D). Here, we examined the effect of varying hepatic glycogen content on the counterregulatory response to low blood sugar in dogs. During the first 4 hours of each study, hepat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Winnick, Jason J., Kraft, Guillaume, Gregory, Justin M., Edgerton, Dale S., Williams, Phillip, Hajizadeh, Ian A., Kamal, Maahum Z., Smith, Marta, Farmer, Ben, Scott, Melanie, Neal, Doss, Donahue, E. Patrick, Allen, Eric, Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887181/
https://ncbi.nlm.nih.gov/pubmed/27140398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79895
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