Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs

In rodents, acute brain insulin action reduces blood glucose levels by suppressing the expression of enzymes in the hepatic gluconeogenic pathway, thereby reducing gluconeogenesis and endogenous glucose production (EGP). Whether a similar mechanism is functional in large animals, including humans, i...

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Hlavní autoři: Ramnanan, Christopher J., Saraswathi, Viswanathan, Smith, Marta S., Donahue, E. Patrick, Farmer, Ben, Farmer, Tiffany D., Neal, Doss, Williams, Philip E., Lautz, Margaret, Mari, Andrea, Cherrington, Alan D., Edgerton, Dale S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163950/
https://ncbi.nlm.nih.gov/pubmed/21865644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45472
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