Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection

An effective human immunodeficiency virus type 1 (HIV-1) vaccine is the best solution for halting the acquired immune deficiency syndrome epidemic. Here, we describe the design and preclinical immunogenicity of T-cell vaccine expressing novel immunogens tHIVconsvX, vectored by DNA, simian (chimpanze...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Ondondo, Beatrice, Murakoshi, Hayato, Clutton, Genevieve, Abdul-Jawad, Sultan, Wee, Edmund G-T, Gatanaga, Hiroyuki, Oka, Shinichi, McMichael, Andrew J, Takiguchi, Masafumi, Korber, Bette, Hanke, Tomáš
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886941/
https://ncbi.nlm.nih.gov/pubmed/26743582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires