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Gene Insertion Into Genomic Safe Harbors for Human Gene Therapy

Genomic safe harbors (GSHs) are sites in the genome able to accommodate the integration of new genetic material in a manner that ensures that the newly inserted genetic elements: (i) function predictably and (ii) do not cause alterations of the host genome posing a risk to the host cell or organism....

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Papapetrou, Eirini P, Schambach, Axel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886940/
https://ncbi.nlm.nih.gov/pubmed/26867951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.38
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