New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion

This study identified 35 new sites for targeted transgene insertion that have the potential to serve as new human genomic “safe harbor” sites (SHS). SHS potential for these 35 sites, located on 16 chromosomes, including both arms of the human X chromosome, and for the existing human SHS AAVS1, hROSA...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Pellenz, Stefan, Phelps, Michael, Tang, Weiliang, Hovde, Blake T., Sinit, Ryan B., Fu, Wenqing, Li, Hui, Chen, Eleanor, Monnat, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648220/
https://ncbi.nlm.nih.gov/pubmed/30793977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.169
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