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New Human Chromosomal Sites with “Safe Harbor” Potential for Targeted Transgene Insertion

This study identified 35 new sites for targeted transgene insertion that have the potential to serve as new human genomic “safe harbor” sites (SHS). SHS potential for these 35 sites, located on 16 chromosomes, including both arms of the human X chromosome, and for the existing human SHS AAVS1, hROSA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther
Hauptverfasser: Pellenz, Stefan, Phelps, Michael, Tang, Weiliang, Hovde, Blake T., Sinit, Ryan B., Fu, Wenqing, Li, Hui, Chen, Eleanor, Monnat, Raymond J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc., publishers 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648220/
https://ncbi.nlm.nih.gov/pubmed/30793977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.169
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