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Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells

While a variety of short interfering RNA (siRNA) delivery compounds have been developed, a deep understanding of the key parameters that determine the quality of siRNA delivery are not known with certainty. Therefore, an understanding of the factors required for the efficient, selective, and safe de...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Sato, Yusuke, Hatakeyama, Hiroto, Hyodo, Mamoru, Harashima, Hideyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886930/
https://ncbi.nlm.nih.gov/pubmed/26678452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.222
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