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Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells

While a variety of short interfering RNA (siRNA) delivery compounds have been developed, a deep understanding of the key parameters that determine the quality of siRNA delivery are not known with certainty. Therefore, an understanding of the factors required for the efficient, selective, and safe de...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sato, Yusuke, Hatakeyama, Hiroto, Hyodo, Mamoru, Harashima, Hideyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886930/
https://ncbi.nlm.nih.gov/pubmed/26678452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.222
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