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Small-sized, stable lipid nanoparticle for the efficient delivery of siRNA to human immune cell lines

Gene silencing by small interfering RNA (siRNA) is useful for analyzing the functions of human immune cells. However, the transfection of siRNA to human immune cells is difficult. Here, we used a multifunctional envelope-type nanodevice (MEND) containing YSK12-C4 (YSK12-MEND) to efficiently introduc...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Nakamura, Takashi, Kuroi, Moeka, Fujiwara, Yuki, Warashina, Shota, Sato, Yusuke, Harashima, Hideyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124971/
https://ncbi.nlm.nih.gov/pubmed/27892533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37849
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