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CD28 Negative T cells: is their loss our gain?

CD28 is a primary costimulation molecule for T cell activation. However, during the course of activation some T cells lose this molecule and assume a CD28-independent existence. These CD28(−) T cells are generally antigen-experienced and highly differentiated. CD28(−) T cells are functionally hetero...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transplant
Hauptverfasser: Mou, Danny, Espinosa, Jaclyn, Lo, Denise J., Kirk, Allan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886707/
https://ncbi.nlm.nih.gov/pubmed/25323029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12937
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