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Functional Characteristics and Phenotypic Plasticity of CD57+PD1− CD4 T Cells and Their Relationship with Transplant Immunosuppression

Costimulation blockade (CoB)-based immunosuppression offers the promise of improved transplantation outcomes with reduced drug toxicity. However, it is hampered by early acute rejections, mediated at least in part by differentiated, CoB resistant T cells, such as CD57+PD1− CD4 T cells. Herein, we ch...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Shaw, Brian I, Espinosa, Jaclyn R, Stempora, Linda, Miller, Allison, Adams, Bartley, Kirk, Allan D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987798/
https://ncbi.nlm.nih.gov/pubmed/33597150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000736
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