CD57(+) CD4 T cells underlie belatacept-resistant allograft rejection

Belatacept is a B7-specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent acute rejection in a sizable minority of patients. In experimental models, memory T cells mediate costimulation blockade-resistant rejection (Co...

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Bibliografiske detaljer
Udgivet i:Am J Transplant
Main Authors: Espinosa, Jaclyn, Herr, Florence, Tharp, Gregory, Bosinger, Steven, Song, Mingqing, Farris, Alton Brad, George, Roshan, Cheeseman, Jennifer, Stempora, Linda, Townsend, Robert, Durrbach, Antoine, Kirk, Allan D.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867077/
https://ncbi.nlm.nih.gov/pubmed/26603381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13613
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