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CD57(+) CD4 T cells underlie belatacept-resistant allograft rejection
Belatacept is a B7-specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent acute rejection in a sizable minority of patients. In experimental models, memory T cells mediate costimulation blockade-resistant rejection (Co...
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Publicado en: | Am J Transplant |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867077/ https://ncbi.nlm.nih.gov/pubmed/26603381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13613 |
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