Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens

BACKGROUND: Chronic ethanol exposure reduces dopamine transmission in the nucleus accumbens, which may contribute to the negative affective symptoms associated with ethanol withdrawal. Kappa opioid receptors have been implicated in withdrawal-induced excessive drinking and anxiety-like behaviors and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Rose, Jamie H., Karkhanis, Anushree N., Chen, Rong, Gioia, Dominic, Lopez, Marcelo F., Becker, Howard C., McCool, Brian A., Jones, Sara R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886667/
https://ncbi.nlm.nih.gov/pubmed/26625893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv127
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados