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Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation
In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity. Although much is known about the development of fibrosis and chronic inflammation in muscular dystrophy, less is known about how they are mecha...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886533/ https://ncbi.nlm.nih.gov/pubmed/27241590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24708 |
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