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Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation

In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity. Although much is known about the development of fibrosis and chronic inflammation in muscular dystrophy, less is known about how they are mecha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Arecco, N., Clarke, C. J., Jones, F. K., Simpson, D. M., Mason, D., Beynon, R. J., Pisconti, A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886533/
https://ncbi.nlm.nih.gov/pubmed/27241590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24708
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