Chronic Hyperinsulinemia Increases Myoblast Proliferation in Fetal Sheep Skeletal Muscle

Insulin is an important fetal growth factor. However, chronic experimental hyperinsulinemia in the fetus fails to accelerate linear and lean mass growth beyond normal rates. Mechanisms preventing accelerated lean mass accretion during hyperinsulinemia are unknown. To address potential mechanisms, la...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Brown, Laura D., Wesolowski, Stephanie R., Kailey, Jenai, Bourque, Stephanie, Wilson, Averi, Andrews, Sasha E., Hay, William W., Rozance, Paul J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891788/
https://ncbi.nlm.nih.gov/pubmed/27049667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1744
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