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Early pancreatic islet fate and maturation is controlled through RBP-Jκ
Notch signaling is known to control early pancreatic differentiation through Ngn3 repression. In later stages, downstream of Notch, the Presenilins are still required to maintain the endocrine fate allocation. Amongst their multiple targets, it remains unclear which one actually controls the mainten...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886527/ https://ncbi.nlm.nih.gov/pubmed/27240887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26874 |
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