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The interaction between KSHV RTA and cellular RBP-Jκ and their subsequent DNA binding are not sufficient for activation of RBP-Jκ

Kaposi’s sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In a...

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Autors principals: Papugani, Anil, Coleman, Tricia, Jones, Clinton, Zhang, Luwen
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225583/
https://ncbi.nlm.nih.gov/pubmed/17850910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2007.07.019
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