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KSHV lytic proteins K-RTA and K8 bind to cellular and viral chromatin to modulate gene expression

The oncogenic Kaposi’s sarcoma-associated herpesvirus (KSHV) has two distinct life cycles with lifelong latent/non-productive and a sporadic lytic-reactivating/productive phases in the infected immune compromised human hosts. The virus reactivates from latency in response to various chemical or envi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kaul, Rajeev, Purushothaman, Pravinkumar, Uppal, Timsy, Verma, Subhash C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472759/
https://ncbi.nlm.nih.gov/pubmed/30998737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215394
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