KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation

Kaposi’s sarcoma associated herpesvirus (KSHV) persists in a highly-ordered chromatin structure inside latently infected cells with the majority of the viral genome having repressive marks. However, upon reactivation the viral chromatin landscape changes into ‘open’ chromatin through the involvement...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Strahan, Roxanne C., McDowell-Sargent, Maria, Uppal, Timsy, Purushothaman, Pravinkumar, Verma, Subhash C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513536/
https://ncbi.nlm.nih.gov/pubmed/28678843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006482
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