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SWI/SNF mutant cancers depend upon catalytic and non–catalytic activity of EZH2
Human cancer genome sequencing has recently revealed that genes encoding subunits of SWI/SNF chromatin remodeling complexes are frequently mutated across a wide variety of cancers, and several subunits of the complex have been shown to have bona fide tumor suppressor activity(1). However, whether mu...
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| 出版年: | Nat Med |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886303/ https://ncbi.nlm.nih.gov/pubmed/26552009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3968 |
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