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Phospho-ubiquitin: upending the PINK–Parkin–ubiquitin cascade
Mitochondria with decreased membrane potential are characterized by defects in protein import into the matrix and impairments in high-efficiency synthesis of ATP. These low-quality mitochondria are marked with ubiquitin for selective degradation. Key factors in this mechanism are PTEN-induced putati...
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| Publicado no: | J Biochem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4885936/ https://ncbi.nlm.nih.gov/pubmed/26839319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvv125 |
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