Genomic Rearrangements and Functional Diversification of lecA and lecB Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed against Pseudomonas aeruginosa

LecA and LecB tetrameric lectins take part in oligosaccharide-mediated adhesion-processes of Pseudomonas aeruginosa. Glycomimetics have been designed to block these interactions. The great versatility of P. aeruginosa suggests that the range of application of these glycomimetics could be restricted...

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Udgivet i:Front Microbiol
Main Authors: Boukerb, Amine M., Decor, Aude, Ribun, Sébastien, Tabaroni, Rachel, Rousset, Audric, Commin, Loris, Buff, Samuel, Doléans-Jordheim, Anne, Vidal, Sébastien, Varrot, Annabelle, Imberty, Anne, Cournoyer, Benoit
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885879/
https://ncbi.nlm.nih.gov/pubmed/27303392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00811
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