Loading...
ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT
The crizotinib-resistant ALK(F1174L) mutation arises de novo in neuroblastoma (NB) and is acquired in ALK translocation-driven cancers, lending impetus to the development of novel anaplastic lymphoma kinase (ALK) inhibitors with different modes of action. The diaminopyrimidine TAE684 and its derivat...
Na minha lista:
| Udgivet i: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4885798/ https://ncbi.nlm.nih.gov/pubmed/26616860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.434 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|