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Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy

We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF(16)Pc. The resulting nanoconjugates can efficiently home to 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and tumour metastasis.

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Detalles Bibliográficos
Publicado en:Nanoscale
Autores principales: Zhen, Zipeng, Tang, Wei, Zhang, Weizhong, Xie, Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885642/
https://ncbi.nlm.nih.gov/pubmed/25998995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr01833a
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