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Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy

We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF(16)Pc. The resulting nanoconjugates can efficiently home to 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and tumour metastasis.

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Zhen, Zipeng, Tang, Wei, Zhang, Weizhong, Xie, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885642/
https://ncbi.nlm.nih.gov/pubmed/25998995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr01833a
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