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Folic acid conjugated ferritins as photosensitizer carriers for photodynamic therapy

We coupled folic acid as a tumour targeting ligand to the surface of ferritins and loaded them with ZnF(16)Pc. The resulting nanoconjugates can efficiently home to 4T1 tumours in vivo, and, with photoirradiation, leading to suppressed tumour growth and tumour metastasis.

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Bibliographic Details
Published in:Nanoscale
Main Authors: Zhen, Zipeng, Tang, Wei, Zhang, Weizhong, Xie, Jin
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885642/
https://ncbi.nlm.nih.gov/pubmed/25998995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr01833a
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