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Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor

Activation of G protein-coupled receptors results in multiple waves of signaling that are mediated by heterotrimeric G proteins and the scaffolding proteins β-arrestin 1/2. Ligands can elicit full or subsets of cellular responses, a concept defined as ligand bias or functional selectivity. However,...

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Detaylı Bibliyografya
Yayımlandı:Mol Pharmacol
Asıl Yazarlar: Delgado-Peraza, Francheska, Ahn, Kwang H., Nogueras-Ortiz, Carlos, Mungrue, Imran N., Mackie, Ken, Kendall, Debra A., Yudowski, Guillermo A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885504/
https://ncbi.nlm.nih.gov/pubmed/27009233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.103176
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