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Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation
Activation of G(s)-coupled receptors enhances engraftment of hematopoietic stem and progenitor cells (HSPCs). We tested the hypothesis that treprostinil, a prostacyclin analog approved for the treatment of pulmonary hypertension, can be repurposed to improve hematopoietic stem cell transplantation....
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| Udgivet i: | Mol Pharmacol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4885501/ https://ncbi.nlm.nih.gov/pubmed/26989084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103267 |
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