Targeting PI3Kδ: One man’s meat is another man’s poison

We have recently uncovered the indispensable role of phosphoinositide-3-kinase δ (PI3Kδ) at different stages of the canonical killing pathway of cytotoxic T lymphocytes (CTLs). The interception of PI3Kδ−conveyed signals has been considered a valuable therapeutic strategy in oncology. However, our ob...

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Bibliographic Details
Main Authors: Prchal-Murphy, Michaela, Putz, Eva Maria, Freissmuth, Michael, Sexl, Veronika, Zebedin-Brandl, Eva
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583912/
https://ncbi.nlm.nih.gov/pubmed/23482629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22272
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