IL-28B down-regulates regulatory T cells but does not improve the protective immunity following tuberculosis subunit vaccine immunization

Regulatory T cells (Tregs), which could be down-regulated by IL-28B, were reported to suppress T-cell-mediated immunity. The aim of this study was to investigate the role of IL-28B on the immune responses and protective efficacy of a tuberculosis (TB) subunit vaccine. First, a recombinant adenoviral...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Luo, Yanping, Ma, Xingming, Liu, Xun, Lu, Xiaoling, Niu, Hongxia, Yu, Hongjuan, Bai, Chunxiang, Peng, Jinxiu, Xian, Qiaoyang, Wang, Yong, Zhu, Bingdong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885220/
https://ncbi.nlm.nih.gov/pubmed/26521300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxv061
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