A multistage mycobacterium tuberculosis subunit vaccine LT70 including latency antigen Rv2626c induces long-term protection against tuberculosis

To develop an effective subunit vaccine which could target tubercle bacilli with different metabolic states and provide effective protective immunity, we fused antigens ESAT6, Ag85B, peptide 190–198 of MPT64, and Mtb8.4 mainly expressed by proliferating bacteria and latency-associated antigen Rv2626...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Liu, Xun, Peng, Jinxiu, Hu, Lina, Luo, Yanping, Niu, Hongxia, Bai, Chunxiang, Wang, Qian, Li, Fei, Yu, Hongjuan, Wang, Bingxiang, Chen, Huiyu, Guo, Ming, Zhu, Bingdong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964814/
https://ncbi.nlm.nih.gov/pubmed/26901244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1141159
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