Multiple direct and indirect mechanisms drive estrogen-induced tumor growth in high grade serous ovarian cancers

The notion that menopausal estrogen replacement therapy increases ovarian cancer risk, but only for the two more common types (i.e. serous and endometrioid), while possibly decreasing risk for clear cell tumors, is strongly suggestive of causality. However, whether estradiol (E(2)) is tumorigenic or...

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Опубликовано в: :Oncotarget
Главные авторы: Ciucci, Alessandra, Zannoni, Gian Franco, Buttarelli, Marianna, Lisi, Lucia, Travaglia, Daniele, Martinelli, Enrica, Scambia, Giovanni, Gallo, Daniela
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884983/
https://ncbi.nlm.nih.gov/pubmed/26797759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6943
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