Multiple direct and indirect mechanisms drive estrogen-induced tumor growth in high grade serous ovarian cancers

The notion that menopausal estrogen replacement therapy increases ovarian cancer risk, but only for the two more common types (i.e. serous and endometrioid), while possibly decreasing risk for clear cell tumors, is strongly suggestive of causality. However, whether estradiol (E(2)) is tumorigenic or...

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Foilsithe in:Oncotarget
Main Authors: Ciucci, Alessandra, Zannoni, Gian Franco, Buttarelli, Marianna, Lisi, Lucia, Travaglia, Daniele, Martinelli, Enrica, Scambia, Giovanni, Gallo, Daniela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884983/
https://ncbi.nlm.nih.gov/pubmed/26797759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6943
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