Multiple direct and indirect mechanisms drive estrogen-induced tumor growth in high grade serous ovarian cancers

The notion that menopausal estrogen replacement therapy increases ovarian cancer risk, but only for the two more common types (i.e. serous and endometrioid), while possibly decreasing risk for clear cell tumors, is strongly suggestive of causality. However, whether estradiol (E(2)) is tumorigenic or...

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Publicado en:Oncotarget
Autores principales: Ciucci, Alessandra, Zannoni, Gian Franco, Buttarelli, Marianna, Lisi, Lucia, Travaglia, Daniele, Martinelli, Enrica, Scambia, Giovanni, Gallo, Daniela
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884983/
https://ncbi.nlm.nih.gov/pubmed/26797759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6943
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