Multiple direct and indirect mechanisms drive estrogen-induced tumor growth in high grade serous ovarian cancers

The notion that menopausal estrogen replacement therapy increases ovarian cancer risk, but only for the two more common types (i.e. serous and endometrioid), while possibly decreasing risk for clear cell tumors, is strongly suggestive of causality. However, whether estradiol (E(2)) is tumorigenic or...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Ciucci, Alessandra, Zannoni, Gian Franco, Buttarelli, Marianna, Lisi, Lucia, Travaglia, Daniele, Martinelli, Enrica, Scambia, Giovanni, Gallo, Daniela
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884983/
https://ncbi.nlm.nih.gov/pubmed/26797759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6943
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